diff --git a/cms/envs/common.py b/cms/envs/common.py
index 5c2adfcf06..fd75914df1 100644
--- a/cms/envs/common.py
+++ b/cms/envs/common.py
@@ -923,9 +923,6 @@ INSTALLED_APPS = [
     # Monitor the status of services
     'openedx.core.djangoapps.service_status',
 
-    # Testing
-    'django_nose',
-
     # Bookmarks
     'openedx.core.djangoapps.bookmarks',
 
diff --git a/cms/envs/test.py b/cms/envs/test.py
index 051b10c293..5657ecd1b8 100644
--- a/cms/envs/test.py
+++ b/cms/envs/test.py
@@ -45,9 +45,6 @@ MONGO_HOST = os.environ.get('EDXAPP_TEST_MONGO_HOST', 'localhost')
 
 THIS_UUID = uuid4().hex[:5]
 
-# Nose Test Runner
-TEST_RUNNER = 'openedx.core.djangolib.nose.NoseTestSuiteRunner'
-
 _SYSTEM = 'cms'
 
 _REPORT_DIR = REPO_ROOT / 'reports' / _SYSTEM
diff --git a/lms/envs/common.py b/lms/envs/common.py
index 05e207872d..b04a2b637c 100644
--- a/lms/envs/common.py
+++ b/lms/envs/common.py
@@ -2090,7 +2090,6 @@ INSTALLED_APPS = [
 
     # For testing
     'django.contrib.admin',  # only used in DEBUG mode
-    'django_nose',
     'debug',
     'django_extensions',
 
diff --git a/lms/envs/test.py b/lms/envs/test.py
index 9841b39976..83eb021ad4 100644
--- a/lms/envs/test.py
+++ b/lms/envs/test.py
@@ -91,9 +91,6 @@ PARENTAL_CONSENT_AGE_LIMIT = 13
 # Makes the tests run much faster...
 SOUTH_TESTS_MIGRATE = False  # To disable migrations and use syncdb instead
 
-# Nose Test Runner
-TEST_RUNNER = 'openedx.core.djangolib.nose.NoseTestSuiteRunner'
-
 _SYSTEM = 'lms'
 
 _REPORT_DIR = REPO_ROOT / 'reports' / _SYSTEM
diff --git a/openedx/core/djangolib/nose.py b/openedx/core/djangolib/nose.py
deleted file mode 100644
index 116456ceda..0000000000
--- a/openedx/core/djangolib/nose.py
+++ /dev/null
@@ -1,30 +0,0 @@
-"""
-Utilities related to nose.
-"""
-import django_nose
-from django.core.management import call_command
-from django.db import DEFAULT_DB_ALIAS, connections, transaction
-
-
-class NoseTestSuiteRunner(django_nose.NoseTestSuiteRunner):
-    """Custom NoseTestSuiteRunner."""
-
-    def setup_databases(self):
-        """ Setup databases and then flush to remove data added by migrations. """
-        return_value = super(NoseTestSuiteRunner, self).setup_databases()
-
-        # Delete all data added by data migrations. Unit tests should setup their own data using factories.
-        call_command('flush', verbosity=0, interactive=False, load_initial_data=False)
-
-        # Through Django 1.8, auto increment sequences are not reset when calling flush on a SQLite db.
-        # So we do it ourselves.
-        # http://sqlite.org/autoinc.html
-        connection = connections[DEFAULT_DB_ALIAS]
-        if connection.vendor == 'sqlite' and not connection.features.supports_sequence_reset:
-            with transaction.atomic(using=DEFAULT_DB_ALIAS):
-                cursor = connection.cursor()
-                cursor.execute(
-                    "delete from sqlite_sequence;"
-                )
-
-        return return_value