diff --git a/cms/djangoapps/contentstore/tests/tests.py b/cms/djangoapps/contentstore/tests/tests.py
index 128672b93b..417b69cfdd 100644
--- a/cms/djangoapps/contentstore/tests/tests.py
+++ b/cms/djangoapps/contentstore/tests/tests.py
@@ -319,7 +319,7 @@ class AuthTestCase(ContentStoreTestCase):
         is turned off
         """
         response = self.client.get(reverse('homepage'))
-        self.assertNotIn('<a class="action action-signup" href="/signup">Sign Up</a>', response.content)
+        self.assertNotContains(response, '<a class="action action-signup" href="/signup">Sign Up</a>')
 
     @mock.patch.dict(settings.FEATURES, {"ALLOW_PUBLIC_ACCOUNT_CREATION": False})
     def test_signup_button_login_page(self):
@@ -328,7 +328,7 @@ class AuthTestCase(ContentStoreTestCase):
         is turned off
         """
         response = self.client.get(reverse('login'))
-        self.assertNotIn('<a class="action action-signup" href="/signup">Sign Up</a>', response.content)
+        self.assertNotContains(response, '<a class="action action-signup" href="/signup">Sign Up</a>')
 
     @mock.patch.dict(settings.FEATURES, {"ALLOW_PUBLIC_ACCOUNT_CREATION": False})
     def test_signup_link_login_page(self):
diff --git a/lms/djangoapps/branding/tests/test_page.py b/lms/djangoapps/branding/tests/test_page.py
index 2b5812388f..6495bcb4c8 100644
--- a/lms/djangoapps/branding/tests/test_page.py
+++ b/lms/djangoapps/branding/tests/test_page.py
@@ -202,15 +202,15 @@ class IndexPageCourseCardsSortingTests(ModuleStoreTestCase):
         response = self.client.get('/')
         self.assertEqual(response.status_code, 200)
         # assert that the course discovery UI is not present
-        self.assertNotIn('Search for a course', response.content)
+        self.assertNotContains(response, 'Search for a course')
 
         # check the /courses view
         response = self.client.get(reverse('courses'))
         self.assertEqual(response.status_code, 200)
 
         # assert that the course discovery UI is not present
-        self.assertNotIn('Search for a course', response.content)
-        self.assertNotIn('<aside aria-label="Refine Your Search" class="search-facets phone-menu">', response.content)
+        self.assertNotContains(response, 'Search for a course')
+        self.assertNotContains(response, '<aside aria-label="Refine Your Search" class="search-facets phone-menu">')
 
         # make sure we have the special css class on the section
         self.assertContains(response, '<div class="courses no-course-discovery"')
diff --git a/lms/djangoapps/certificates/tests/test_webview_views.py b/lms/djangoapps/certificates/tests/test_webview_views.py
index 81c6e4d85b..9663d817e3 100644
--- a/lms/djangoapps/certificates/tests/test_webview_views.py
+++ b/lms/djangoapps/certificates/tests/test_webview_views.py
@@ -942,14 +942,14 @@ class CertificatesViewsTests(CommonCertificatesTestCase, CacheIsolationTestCase)
         CourseStaffRole(self.course.id).add_users(self.user)
 
         response = self.client.get(test_url + '?preview=honor')
-        self.assertNotIn(self.course.display_name.encode('utf-8'), response.content)
+        self.assertNotContains(response, self.course.display_name.encode('utf-8'))
         self.assertIn('course_title_0', response.content.decode('utf-8'))
         self.assertIn('Signatory_Title 0', response.content.decode('utf-8'))
 
         # mark certificate inactive but accessing in preview mode.
         self._add_course_certificates(count=1, signatory_count=2, is_active=False)
         response = self.client.get(test_url + '?preview=honor')
-        self.assertNotIn(self.course.display_name.encode('utf-8'), response.content)
+        self.assertNotContains(response, self.course.display_name.encode('utf-8'))
         self.assertIn('course_title_0', response.content.decode('utf-8'))
         self.assertIn('Signatory_Title 0', response.content.decode('utf-8'))
 
@@ -970,7 +970,7 @@ class CertificatesViewsTests(CommonCertificatesTestCase, CacheIsolationTestCase)
         # user has already has certificate generated for 'honor' mode
         # so let's try to preview in 'verified' mode.
         response = self.client.get(test_url + '?preview=verified')
-        self.assertNotIn(self.course.display_name.encode('utf-8'), response.content)
+        self.assertNotContains(response, self.course.display_name.encode('utf-8'))
         self.assertIn('course_title_0', response.content.decode('utf-8'))
         self.assertIn('Signatory_Title 0', response.content.decode('utf-8'))
 
diff --git a/lms/djangoapps/courseware/tests/test_date_summary.py b/lms/djangoapps/courseware/tests/test_date_summary.py
index 6466636de1..6063ebd335 100644
--- a/lms/djangoapps/courseware/tests/test_date_summary.py
+++ b/lms/djangoapps/courseware/tests/test_date_summary.py
@@ -61,7 +61,7 @@ class CourseDateSummaryTest(SharedModuleStoreTestCase):
         self.client.login(username=user.username, password=TEST_PASSWORD)
         url = reverse('info', args=(course.id,))
         response = self.client.get(url)
-        self.assertNotIn(b'date-summary', response.content)
+        self.assertNotContains(response, 'date-summary', status_code=302)
 
     def test_course_home_logged_out(self):
         course = create_course_run()
diff --git a/lms/djangoapps/courseware/tests/test_views.py b/lms/djangoapps/courseware/tests/test_views.py
index 9ba3af18fe..63f91191f1 100644
--- a/lms/djangoapps/courseware/tests/test_views.py
+++ b/lms/djangoapps/courseware/tests/test_views.py
@@ -395,8 +395,8 @@ class ViewsTestCase(ModuleStoreTestCase):
         )
         response = self.client.get(url)
         self.assertEqual(response.status_code, 200)
-        self.assertNotIn('Problem 1', response.content)
-        self.assertNotIn('Problem 2', response.content)
+        self.assertNotContains(response, 'Problem 1')
+        self.assertNotContains(response, 'Problem 2')
 
     def _create_global_staff_user(self):
         """
@@ -467,13 +467,13 @@ class ViewsTestCase(ModuleStoreTestCase):
         self.client.logout()
         response = self.client.get(reverse('about_course', args=[six.text_type(course.id)]))
         self.assertEqual(response.status_code, 200)
-        self.assertNotIn(in_cart_span, response.content)
+        self.assertNotContains(response, in_cart_span)
 
         # authenticated user with nothing in cart
         self.assertTrue(self.client.login(username=self.user.username, password=TEST_PASSWORD))
         response = self.client.get(reverse('about_course', args=[six.text_type(course.id)]))
         self.assertEqual(response.status_code, 200)
-        self.assertNotIn(in_cart_span, response.content)
+        self.assertNotContains(response, in_cart_span)
 
         # now add the course to the cart
         cart = shoppingcart.models.Order.get_cart_for_user(self.user)
@@ -628,7 +628,7 @@ class ViewsTestCase(ModuleStoreTestCase):
         })
         response = self.client.get(url)
         # Tests that we do not get an "Invalid x" response when passing correct arguments to view
-        self.assertNotIn('Invalid', response.content)
+        self.assertNotContains(response, 'Invalid')
 
     def test_submission_history_xss(self):
         # log into a staff account
@@ -643,7 +643,7 @@ class ViewsTestCase(ModuleStoreTestCase):
             'location': '<script>alert("hello");</script>'
         })
         response = self.client.get(url)
-        self.assertNotIn('<script>', response.content)
+        self.assertNotContains(response, '<script>')
 
         # try it with a malicious user and a non-existent location
         url = reverse('submission_history', kwargs={
@@ -652,7 +652,7 @@ class ViewsTestCase(ModuleStoreTestCase):
             'location': 'dummy'
         })
         response = self.client.get(url)
-        self.assertNotIn('<script>', response.content)
+        self.assertNotContains(response, '<script>')
 
     def test_submission_history_contents(self):
         # log into a staff account
@@ -786,7 +786,7 @@ class ViewsTestCase(ModuleStoreTestCase):
         response = self.client.get(url)
         self.assertEqual(response.status_code, 200)
 
-        self.assertNotIn(str(course.id), response.content)
+        self.assertNotContains(response, str(course.id))
 
     @patch.object(CourseOverview, 'load_from_module_store', return_value=None)
     def test_financial_assistance_form_missing_course_overview(self, _mock_course_overview):
@@ -815,7 +815,7 @@ class ViewsTestCase(ModuleStoreTestCase):
         response = self.client.get(url)
         self.assertEqual(response.status_code, 200)
 
-        self.assertNotIn(str(course), response.content)
+        self.assertNotContains(response, str(course))
 
     def test_financial_assistance_form(self):
         """Verify that learner can get the financial aid for the course in which
@@ -2630,10 +2630,10 @@ class TestIndexViewCompleteOnView(ModuleStoreTestCase, CompletionWaffleTestMixin
         self.assertTrue(self.client.login(username=self.user.username, password='test'))
 
         response = self.client.get(self.section_1_url)
-        self.assertNotIn('data-mark-completed-on-view-after-delay', response.content)
+        self.assertNotContains(response, 'data-mark-completed-on-view-after-delay')
 
         response = self.client.get(self.section_2_url)
-        self.assertNotIn('data-mark-completed-on-view-after-delay', response.content)
+        self.assertNotContains(response, 'data-mark-completed-on-view-after-delay')
 
     @ddt.data(ModuleStoreEnum.Type.mongo, ModuleStoreEnum.Type.split)
     def test_completion_service_enabled(self, default_store):
@@ -2680,10 +2680,10 @@ class TestIndexViewCompleteOnView(ModuleStoreTestCase, CompletionWaffleTestMixin
         self.assertEqual(json.loads(response.content.decode('utf-8')), {'result': "ok"})
 
         response = self.client.get(self.section_1_url)
-        self.assertNotIn('data-mark-completed-on-view-after-delay', response.content)
+        self.assertNotContains(response, 'data-mark-completed-on-view-after-delay')
 
         response = self.client.get(self.section_2_url)
-        self.assertNotIn('data-mark-completed-on-view-after-delay', response.content)
+        self.assertNotContains(response, 'data-mark-completed-on-view-after-delay')
 
 
 @ddt.ddt
@@ -2906,7 +2906,7 @@ class TestRenderXBlock(RenderXBlockTestMixin, ModuleStoreTestCase, CompletionWaf
         response = self.get_response(usage_key=self.html_block.location)
         self.assertEqual(response.status_code, 200)
         self.assertContains(response, 'data-enable-completion-on-view-service="false"')
-        self.assertNotIn('data-mark-completed-on-view-after-delay', response.content)
+        self.assertNotContains(response, 'data-mark-completed-on-view-after-delay')
 
     def test_render_xblock_with_completion_service_enabled(self):
         """
@@ -2940,12 +2940,12 @@ class TestRenderXBlock(RenderXBlockTestMixin, ModuleStoreTestCase, CompletionWaf
         response = self.get_response(usage_key=self.html_block.location)
         self.assertEqual(response.status_code, 200)
         self.assertContains(response, 'data-enable-completion-on-view-service="false"')
-        self.assertNotIn('data-mark-completed-on-view-after-delay', response.content)
+        self.assertNotContains(response, 'data-mark-completed-on-view-after-delay')
 
         response = self.get_response(usage_key=self.problem_block.location)
         self.assertEqual(response.status_code, 200)
         self.assertContains(response, 'data-enable-completion-on-view-service="false"')
-        self.assertNotIn('data-mark-completed-on-view-after-delay', response.content)
+        self.assertNotContains(response, 'data-mark-completed-on-view-after-delay')
 
 
 class TestRenderXBlockSelfPaced(TestRenderXBlock):
diff --git a/lms/djangoapps/instructor/tests/test_ecommerce.py b/lms/djangoapps/instructor/tests/test_ecommerce.py
index d9290caf43..3318f8ce9a 100644
--- a/lms/djangoapps/instructor/tests/test_ecommerce.py
+++ b/lms/djangoapps/instructor/tests/test_ecommerce.py
@@ -73,7 +73,7 @@ class TestECommerceDashboardViews(SiteMixin, SharedModuleStoreTestCase):
         """
         response = self.client.get(self.url)
         self.assertContains(response, self.ecommerce_link)
-        self.assertNotIn('Create Enrollment Report', response.content)
+        self.assertNotContains(response, 'Create Enrollment Report')
 
     def test_user_has_finance_admin_rights_in_e_commerce_tab(self):
         response = self.client.get(self.url)
@@ -90,7 +90,7 @@ class TestECommerceDashboardViews(SiteMixin, SharedModuleStoreTestCase):
         # Order/Invoice sales csv button text should not be visible in e-commerce page if the user is not finance admin
         url = reverse('instructor_dashboard', kwargs={'course_id': text_type(self.course.id)})
         response = self.client.post(url)
-        self.assertNotIn('Download All Invoices', response.content)
+        self.assertNotContains(response, 'Download All Invoices')
 
     def test_user_view_course_price(self):
         """
@@ -105,7 +105,7 @@ class TestECommerceDashboardViews(SiteMixin, SharedModuleStoreTestCase):
 
         price = course_honor_mode.min_price
         self.assertContains(response, 'Course price per seat: <span>$' + str(price) + '</span>')
-        self.assertNotIn('+ Set Price</a></span>', response.content)
+        self.assertNotContains(response, '+ Set Price</a></span>')
 
         # removing the course finance_admin role of login user
         CourseFinanceAdminRole(self.course.id).remove_users(self.instructor)
@@ -113,7 +113,7 @@ class TestECommerceDashboardViews(SiteMixin, SharedModuleStoreTestCase):
         # total amount should not be visible in e-commerce page if the user is not finance admin
         url = reverse('instructor_dashboard', kwargs={'course_id': text_type(self.course.id)})
         response = self.client.get(url)
-        self.assertNotIn('+ Set Price</a></span>', response.content)
+        self.assertNotContains(response, '+ Set Price</a></span>')
 
     def test_update_course_price_check(self):
         price = 200
@@ -214,7 +214,7 @@ class TestECommerceDashboardViews(SiteMixin, SharedModuleStoreTestCase):
         response = self.client.post(self.url)
         self.assertContains(response, '<td>ADSADASDSAD</td>')
         self.assertContains(response, '<td>A2314</td>')
-        self.assertNotIn('<td>111</td>', response.content)
+        self.assertNotContains(response, '<td>111</td>')
 
         data = {
             'code': 'A2345314', 'course_id': text_type(self.course.id),
@@ -376,7 +376,7 @@ class TestECommerceDashboardViews(SiteMixin, SharedModuleStoreTestCase):
         response = self.client.get(self.url)
         self.assertContains(response, self.ecommerce_link)
         # Coupons should show up for White Label sites with priced honor modes.
-        self.assertNotIn('Coupons List', response.content)
+        self.assertNotContains(response, 'Coupons List')
 
     def test_coupon_code_section_not_under_e_commerce_tab(self):
         """
@@ -388,7 +388,7 @@ class TestECommerceDashboardViews(SiteMixin, SharedModuleStoreTestCase):
 
         response = self.client.get(self.url)
         self.assertContains(response, self.ecommerce_link)
-        self.assertNotIn('Coupon Code List', response.content)
+        self.assertNotContains(response, 'Coupon Code List')
 
     def test_enrollment_codes_section_not_under_e_commerce_tab(self):
         """
@@ -400,7 +400,7 @@ class TestECommerceDashboardViews(SiteMixin, SharedModuleStoreTestCase):
 
         response = self.client.get(self.url)
         self.assertContains(response, self.ecommerce_link)
-        self.assertNotIn('<h3 class="hd hd-3">Enrollment Codes</h3>', response.content)
+        self.assertNotContains(response, '<h3 class="hd hd-3">Enrollment Codes</h3>')
 
     def test_enrollment_codes_section_visible_for_non_ecommerce_course(self):
         """
diff --git a/lms/djangoapps/instructor/tests/test_email.py b/lms/djangoapps/instructor/tests/test_email.py
index 66553c516d..3fec3bce12 100644
--- a/lms/djangoapps/instructor/tests/test_email.py
+++ b/lms/djangoapps/instructor/tests/test_email.py
@@ -66,7 +66,7 @@ class TestNewInstructorDashboardEmailViewMongoBacked(SharedModuleStoreTestCase):
         BulkEmailFlag.objects.create(enabled=False)
         # Assert that the URL for the email view is not in the response
         response = self.client.get(self.url)
-        self.assertNotIn(self.email_link, response.content)
+        self.assertNotContains(response, self.email_link)
 
     # Flag is enabled, but we require course auth and haven't turned it on for this course
     def test_course_not_authorized(self):
@@ -75,7 +75,7 @@ class TestNewInstructorDashboardEmailViewMongoBacked(SharedModuleStoreTestCase):
         self.assertFalse(is_bulk_email_feature_enabled(self.course.id))
         # Assert that the URL for the email view is not in the response
         response = self.client.get(self.url)
-        self.assertNotIn(self.email_link, response.content)
+        self.assertNotContains(response, self.email_link)
 
     # Flag is enabled, we require course auth and turn it on for this course
     def test_course_authorized(self):
@@ -84,7 +84,7 @@ class TestNewInstructorDashboardEmailViewMongoBacked(SharedModuleStoreTestCase):
         self.assertFalse(is_bulk_email_feature_enabled(self.course.id))
         # Assert that the URL for the email view is not in the response
         response = self.client.get(self.url)
-        self.assertNotIn(self.email_link, response.content)
+        self.assertNotContains(response, self.email_link)
 
         # Authorize the course to use email
         cauth = CourseAuthorization(course_id=self.course.id, email_enabled=True)
@@ -108,7 +108,7 @@ class TestNewInstructorDashboardEmailViewMongoBacked(SharedModuleStoreTestCase):
         self.assertTrue(is_bulk_email_enabled_for_course(self.course.id))
         # Assert that the URL for the email view IS NOT in the response
         response = self.client.get(self.url)
-        self.assertNotIn(self.email_link, response.content)
+        self.assertNotContains(response, self.email_link)
 
 
 class TestNewInstructorDashboardEmailViewXMLBacked(SharedModuleStoreTestCase):
@@ -149,10 +149,10 @@ class TestNewInstructorDashboardEmailViewXMLBacked(SharedModuleStoreTestCase):
     def test_email_flag_true_mongo_false(self):
         BulkEmailFlag.objects.create(enabled=True, require_course_email_auth=False)
         response = self.client.get(self.url)
-        self.assertNotIn(self.email_link, response.content)
+        self.assertNotContains(response, self.email_link, status_code=404)
 
     # The flag is disabled and the course is not Mongo-backed (should not work)
     def test_email_flag_false_mongo_false(self):
         BulkEmailFlag.objects.create(enabled=False, require_course_email_auth=False)
         response = self.client.get(self.url)
-        self.assertNotIn(self.email_link, response.content)
+        self.assertNotContains(response, self.email_link, status_code=404)
diff --git a/lms/djangoapps/instructor/tests/test_proctoring.py b/lms/djangoapps/instructor/tests/test_proctoring.py
index a4fcc4811b..6cbd129c76 100644
--- a/lms/djangoapps/instructor/tests/test_proctoring.py
+++ b/lms/djangoapps/instructor/tests/test_proctoring.py
@@ -135,7 +135,7 @@ class TestProctoringDashboardViews(SharedModuleStoreTestCase):
         self.setup_course(True, True)
         response = self.client.get(self.url)
         # the default backend does not support the review dashboard
-        self.assertNotIn('Review Dashboard', response.content)
+        self.assertNotContains(response, 'Review Dashboard')
 
         backend = TestBackendProvider()
         config = apps.get_app_config('edx_proctoring')
diff --git a/lms/djangoapps/instructor/tests/views/test_instructor_dashboard.py b/lms/djangoapps/instructor/tests/views/test_instructor_dashboard.py
index f4980f7e07..71b5cb1a8a 100644
--- a/lms/djangoapps/instructor/tests/views/test_instructor_dashboard.py
+++ b/lms/djangoapps/instructor/tests/views/test_instructor_dashboard.py
@@ -215,7 +215,7 @@ class TestInstructorDashboard(ModuleStoreTestCase, LoginEnrollmentTestCase, XssT
         staff = StaffFactory(course_key=self.course.id)
         self.client.login(username=staff.username, password="test")
         response = self.client.get(self.url)
-        self.assertNotIn('<h4 class="hd hd-4">Adjust all enrolled learners', response.content)
+        self.assertNotContains(response, '<h4 class="hd hd-4">Adjust all enrolled learners')
         self.assertContains(response, '<h4 class="hd hd-4">View a specific learner&#39;s grades and progress')
 
     @patch(
@@ -305,7 +305,7 @@ class TestInstructorDashboard(ModuleStoreTestCase, LoginEnrollmentTestCase, XssT
         """
         response = self.client.get(self.url)
         # no enrollment information should be visible
-        self.assertNotIn('<h3 class="hd hd-3">Enrollment Information</h3>', response.content)
+        self.assertNotContains(response, '<h3 class="hd hd-3">Enrollment Information</h3>')
 
     @patch.dict(settings.FEATURES, {'DISPLAY_ANALYTICS_ENROLLMENTS': True})
     @override_settings(ANALYTICS_DASHBOARD_URL='')
@@ -349,10 +349,10 @@ class TestInstructorDashboard(ModuleStoreTestCase, LoginEnrollmentTestCase, XssT
         response = self.client.get(self.url)
 
         # enrollment information hidden
-        self.assertNotIn('<th scope="row">Verified</th>', response.content)
-        self.assertNotIn('<th scope="row">Audit</th>', response.content)
-        self.assertNotIn('<th scope="row">Honor</th>', response.content)
-        self.assertNotIn('<th scope="row">Professional</th>', response.content)
+        self.assertNotContains(response, '<th scope="row">Verified</th>')
+        self.assertNotContains(response, '<th scope="row">Audit</th>')
+        self.assertNotContains(response, '<th scope="row">Honor</th>')
+        self.assertNotContains(response, '<th scope="row">Professional</th>')
 
         # link to dashboard shown
         expected_message = self.get_dashboard_enrollment_message()
@@ -366,7 +366,7 @@ class TestInstructorDashboard(ModuleStoreTestCase, LoginEnrollmentTestCase, XssT
         """
         response = self.client.get(self.url)
         analytics_section = '<li class="nav-item"><a href="" data-section="instructor_analytics">Analytics</a></li>'
-        self.assertNotIn(analytics_section, response.content)
+        self.assertNotContains(response, analytics_section)
 
     @override_settings(ANALYTICS_DASHBOARD_URL='http://example.com')
     @override_settings(ANALYTICS_DASHBOARD_NAME='Example')
@@ -479,7 +479,7 @@ class TestInstructorDashboard(ModuleStoreTestCase, LoginEnrollmentTestCase, XssT
         )
 
         response = self.client.get(self.url)
-        self.assertNotIn(ora_section, response.content)
+        self.assertNotContains(response, ora_section)
 
         ItemFactory.create(parent_location=self.course.location, category="openassessment")
         response = self.client.get(self.url)
diff --git a/openedx/features/announcements/tests/test_announcements.py b/openedx/features/announcements/tests/test_announcements.py
index 99cf50f0ae..1195187610 100644
--- a/openedx/features/announcements/tests/test_announcements.py
+++ b/openedx/features/announcements/tests/test_announcements.py
@@ -54,8 +54,8 @@ class TestGlobalAnnouncements(TestCase):
     def test_feature_flag_disabled(self):
         """Ensures that the default settings effectively disables the feature"""
         response = self.client.get('/dashboard')
-        self.assertNotIn('AnnouncementsView', response.content)
-        self.assertNotIn('<div id="announcements"', response.content)
+        self.assertNotContains(response, 'AnnouncementsView')
+        self.assertNotContains(response, '<div id="announcements"')
 
     def test_feature_flag_enabled(self):
         """Ensures that enabling the flag, enables the feature"""
@@ -87,7 +87,7 @@ class TestGlobalAnnouncements(TestCase):
         """
         url = reverse("announcements:page", kwargs={"page": 1})
         response = self.client.get(url)
-        self.assertNotIn("Inactive Announcement", response.content)
+        self.assertNotContains(response, "Inactive Announcement")
 
     def test_formatted(self):
         """
diff --git a/openedx/features/course_duration_limits/tests/test_course_expiration.py b/openedx/features/course_duration_limits/tests/test_course_expiration.py
index 82d996cece..ed67022b86 100644
--- a/openedx/features/course_duration_limits/tests/test_course_expiration.py
+++ b/openedx/features/course_duration_limits/tests/test_course_expiration.py
@@ -221,7 +221,7 @@ class CourseExpirationTestCase(ModuleStoreTestCase):
         if show_expiration_banner:
             self.assertContains(response, banner_text)
         else:
-            self.assertNotIn(banner_text, response.content)
+            self.assertNotContains(response, banner_text)
 
     def update_masquerade(self, role='student', group_id=None, username=None, user_partition_id=None):
         """
@@ -283,7 +283,7 @@ class CourseExpirationTestCase(ModuleStoreTestCase):
         self.assertEqual(response.status_code, 200)
         six.assertCountEqual(self, response.redirect_chain, [])
         banner_text = 'You lose all access to this course, including your progress,'
-        self.assertNotIn(banner_text, response.content)
+        self.assertNotContains(response, banner_text)
 
     @mock.patch("openedx.features.course_duration_limits.access.get_course_run_details")
     def test_masquerade_expired(self, mock_get_course_run_details):
@@ -370,7 +370,7 @@ class CourseExpirationTestCase(ModuleStoreTestCase):
         self.assertEqual(response.status_code, 200)
         six.assertCountEqual(self, response.redirect_chain, [])
         banner_text = 'This learner does not have access to this course. Their access expired on'
-        self.assertNotIn(banner_text, response.content)
+        self.assertNotContains(response, banner_text)
 
     @mock.patch("openedx.features.course_duration_limits.access.get_course_run_details")
     @ddt.data(
@@ -419,4 +419,4 @@ class CourseExpirationTestCase(ModuleStoreTestCase):
         self.assertEqual(response.status_code, 200)
         six.assertCountEqual(self, response.redirect_chain, [])
         banner_text = 'This learner does not have access to this course. Their access expired on'
-        self.assertNotIn(banner_text, response.content)
+        self.assertNotContains(response, banner_text)
diff --git a/openedx/features/course_experience/tests/views/test_course_home.py b/openedx/features/course_experience/tests/views/test_course_home.py
index a14f4d0a90..0894b92a40 100644
--- a/openedx/features/course_experience/tests/views/test_course_home.py
+++ b/openedx/features/course_experience/tests/views/test_course_home.py
@@ -962,7 +962,7 @@ class CourseHomeFragmentViewTests(ModuleStoreTestCase):
 
     def assert_upgrade_message_not_displayed(self):
         response = self.client.get(self.url)
-        self.assertNotIn('section-upgrade', response.content)
+        self.assertNotContains(response, 'section-upgrade')
 
     def assert_upgrade_message_displayed(self):
         response = self.client.get(self.url)