diff --git a/cms/static/karma_cms.conf.js b/cms/static/karma_cms.conf.js
index 6d6451ebd4..a0fbea97c9 100644
--- a/cms/static/karma_cms.conf.js
+++ b/cms/static/karma_cms.conf.js
@@ -23,7 +23,10 @@ var options = {
     // Make sure the patterns in sourceFiles and specFiles do not match the same file.
     // Otherwise Istanbul which is used for coverage tracking will cause tests to not run.
     sourceFiles: [
-        {pattern: 'cms/**/!(*spec|djangojs).js'},
+        // Split cms/ patterns to exclude spec/main*.js test entry points (handled by runFiles)
+        {pattern: 'cms/js/!(*spec|djangojs).js'},  // Direct children of cms/js/
+        {pattern: 'cms/js/!(spec)/**/!(*spec|djangojs).js'},  // Subdirs of cms/js/ except spec/
+        {pattern: 'cms/js/spec/**/!(*spec|djangojs|main*).js'},  // spec/ subdir, excluding main* files
         {pattern: 'js/**/!(*spec|djangojs).js'}
     ],
 
diff --git a/cms/static/karma_cms_squire.conf.js b/cms/static/karma_cms_squire.conf.js
index 9a83a189be..bde06ecc84 100644
--- a/cms/static/karma_cms_squire.conf.js
+++ b/cms/static/karma_cms_squire.conf.js
@@ -23,7 +23,10 @@ var options = {
     // Make sure the patterns in sourceFiles and specFiles do not match the same file.
     // Otherwise Istanbul which is used for coverage tracking will cause tests to not run.
     sourceFiles: [
-        {pattern: 'cms/js/**/!(*spec|djangojs).js'},
+        // Split cms/js/ patterns to exclude spec/main*.js test entry points (handled by runFiles)
+        {pattern: 'cms/js/!(*spec|djangojs).js'},  // Direct children of cms/js/
+        {pattern: 'cms/js/!(spec)/**/!(*spec|djangojs).js'},  // Subdirs of cms/js/ except spec/
+        {pattern: 'cms/js/spec/**/!(*spec|djangojs|main*).js'},  // spec/ subdir, excluding main* files
         {pattern: 'js/**/!(*spec|djangojs).js'}
     ],
 
diff --git a/common/static/common/js/karma.common.conf.js b/common/static/common/js/karma.common.conf.js
index 91a2d78085..ece7f1b5c4 100644
--- a/common/static/common/js/karma.common.conf.js
+++ b/common/static/common/js/karma.common.conf.js
@@ -60,7 +60,9 @@ var commonFiles = {
     ],
 
     sourceFiles: [
-        {pattern: 'common/js/!(spec_helpers)/**/!(*spec).js'}
+        // Split common/js/ to exclude spec/main*.js test entry points (handled by runFiles)
+        {pattern: 'common/js/!(spec_helpers|spec)/**/!(*spec).js'},  // all non-spec, non-spec_helpers dirs
+        {pattern: 'common/js/spec/**/!(*spec|main*).js'}  // spec dir, excluding spec and main* files
     ],
 
     specFiles: [
diff --git a/lms/static/karma_lms.conf.js b/lms/static/karma_lms.conf.js
index 0119d4d18c..b3b24f631e 100644
--- a/lms/static/karma_lms.conf.js
+++ b/lms/static/karma_lms.conf.js
@@ -34,7 +34,10 @@ var options = {
         {pattern: 'discussion/js/**/!(*spec).js'},
         {pattern: 'js/**/!(*spec|djangojs).js'},
         {pattern: 'learner_profile/**/!(*spec).js'},
-        {pattern: 'lms/js/**/!(*spec).js'},
+        // Split lms/js/ to exclude spec/main*.js test entry points (handled by runFiles)
+        {pattern: 'lms/js/!(*spec).js'},  // Direct children of lms/js/
+        {pattern: 'lms/js/!(spec)/**/!(*spec).js'},  // Subdirs of lms/js/ except spec/
+        {pattern: 'lms/js/spec/**/!(*spec|main*).js'},  // spec/ subdir, excluding main* files
         {pattern: 'support/js/**/!(*spec).js'},
         {pattern: 'teams/js/**/!(*spec).js'},
         {pattern: 'completion/js/**/!(*spec).js'}