diff --git a/common/djangoapps/edxmako/paths.py b/common/djangoapps/edxmako/paths.py
index f7791da090..5a3d00423e 100644
--- a/common/djangoapps/edxmako/paths.py
+++ b/common/djangoapps/edxmako/paths.py
@@ -11,6 +11,7 @@ from django.conf import settings
 from mako.exceptions import TopLevelLookupException
 from mako.lookup import TemplateLookup
 
+from request_cache.middleware import request_cached
 from openedx.core.djangoapps.theming.helpers import get_template as themed_template
 from openedx.core.djangoapps.theming.helpers import get_template_path_with_theme, strip_site_theme_templates_path
 
@@ -107,6 +108,7 @@ def add_lookup(namespace, directory, package=None, prepend=False):
     templates.add_directory(directory, prepend=prepend)
 
 
+@request_cached
 def lookup_template(namespace, name):
     """
     Look up a Mako template by namespace and name.
diff --git a/openedx/core/djangoapps/theming/helpers.py b/openedx/core/djangoapps/theming/helpers.py
index 6aa0d252b3..41152ee747 100644
--- a/openedx/core/djangoapps/theming/helpers.py
+++ b/openedx/core/djangoapps/theming/helpers.py
@@ -19,14 +19,17 @@ from openedx.core.djangoapps.theming.helpers_dirs import (
     get_theme_dirs,
     get_themes_unchecked
 )
-from request_cache.middleware import RequestCache
+from request_cache.middleware import RequestCache, request_cached
 
 logger = getLogger(__name__)  # pylint: disable=invalid-name
 
 
+@request_cached
 def get_template_path(relative_path, **kwargs):
     """
     This is a proxy function to hide microsite_configuration behind comprehensive theming.
+
+    The calculated value is cached for the lifetime of the current request.
     """
     # We need to give priority to theming over microsites
     # So, we apply microsite override only if there is no associated site theme
diff --git a/openedx/core/djangoapps/theming/tests/test_helpers.py b/openedx/core/djangoapps/theming/tests/test_helpers.py
index 96e441004c..fb87596f0f 100644
--- a/openedx/core/djangoapps/theming/tests/test_helpers.py
+++ b/openedx/core/djangoapps/theming/tests/test_helpers.py
@@ -12,6 +12,7 @@ from openedx.core.djangoapps.theming import helpers as theming_helpers
 from openedx.core.djangoapps.theming.helpers import get_template_path_with_theme, strip_site_theme_templates_path, \
     get_themes, Theme, get_theme_base_dir
 from openedx.core.djangolib.testing.utils import skip_unless_cms, skip_unless_lms
+from request_cache.middleware import RequestCache
 
 
 class TestHelpers(TestCase):
@@ -189,6 +190,8 @@ class TestHelpers(TestCase):
                     mock_microsite_backend.get_template = Mock(return_value="/microsite/about.html")
                     self.assertEqual(theming_helpers.get_template_path("about.html"), "about.html")
 
+        RequestCache.clear_request_cache()
+
         # if the current site does not have associated SiteTheme then get_template_path should return microsite override
         with patch(
             "openedx.core.djangoapps.theming.helpers.current_request_has_associated_site_theme",